Stabilizer
Stabilizer refers to a variety of substances or devices that are used to maintain a system or process in a stable condition. In the context of medicine, stabilizers are often used in pharmaceutical products to ensure their chemical stability, physical integrity, and efficacy over time.
Types of Stabilizers in Medicine[edit | edit source]
There are several types of stabilizers used in medicine, including:
- Antioxidants: These are substances that prevent or slow down oxidation reactions, which can lead to the degradation of active pharmaceutical ingredients (APIs). Examples include ascorbic acid, tocopherols, and butylated hydroxyanisole (BHA).
- Chelating agents: These are compounds that can form several bonds with a single metal ion, helping to prevent the degradation of APIs due to metal-catalyzed oxidation. Examples include ethylenediaminetetraacetic acid (EDTA) and citric acid.
- pH stabilizers: These are substances used to maintain the pH of a pharmaceutical product within a certain range, which is often necessary for the stability and efficacy of the APIs. Examples include buffers, acids, and bases.
- Viscosity modifiers: These are substances used to adjust the viscosity of a pharmaceutical product, which can affect its stability, ease of administration, and release of APIs. Examples include cellulose derivatives, polyvinyl alcohol, and xanthan gum.
Applications of Stabilizers in Medicine[edit | edit source]
Stabilizers are used in a wide range of pharmaceutical products, including:
- Tablets and capsules: Stabilizers can help to maintain the physical integrity of these solid dosage forms, as well as the stability and efficacy of the APIs.
- Liquid dosage forms: Stabilizers can help to prevent the degradation of APIs, the growth of microorganisms, and the separation of components in these dosage forms.
- Topical preparations: Stabilizers can help to maintain the consistency and efficacy of these preparations, as well as the stability of the APIs.
- Parenteral preparations: Stabilizers can help to prevent the degradation of APIs, the growth of microorganisms, and the precipitation of components in these sterile dosage forms.
See Also[edit | edit source]
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