Strophanthus kombe

From WikiMD's Food, Medicine & Wellness Encyclopedia

Strophanthus kombe is a species of flowering plant in the Apocynaceae family, native to tropical regions of Africa. It is known for its medicinal properties and as a source of the cardiac glycoside, ouabain, which has been used in traditional medicine and has applications in modern pharmacology. The plant is characterized by its distinctive flowers, which have long, tail-like appendages, and it plays a significant role in the ecosystems where it is found.

Description[edit | edit source]

Strophanthus kombe is a woody vine or small tree that can reach up to several meters in height. The leaves are simple, opposite, and elliptical in shape with a leathery texture. The flowers are large and showy, typically with five white to pink petals that are fused at the base, forming a tube-like structure. The most striking feature of the flowers is the long, slender appendages that extend from the petals, which can be several centimeters in length. The fruit of the plant is a pair of follicles, which contain numerous seeds with a tuft of silky hairs at one end, aiding in wind dispersal.

Distribution and Habitat[edit | edit source]

Strophanthus kombe is found in various parts of tropical Africa, from West Africa to the East African coast and southward to Angola and Zambia. It grows in a range of habitats, including forests, woodland savannas, and along riverbanks, where it can receive ample sunlight.

Uses[edit | edit source]

Historically, Strophanthus kombe has been used in traditional African medicine. The seeds are the most commonly used part of the plant, known for their potent cardiac glycosides, particularly ouabain. These compounds have the ability to increase the force of heart contractions and have been used to treat heart failure and certain arrhythmias. In addition to its medicinal uses, the plant has been used as a poison, particularly for hunting, due to the potent effects of its cardiac glycosides.

In modern pharmacology, ouabain and other compounds extracted from Strophanthus kombe have been studied for their potential therapeutic applications. However, due to the narrow therapeutic index and the availability of other cardiac medications, the use of ouabain has declined in recent years.

Conservation[edit | edit source]

As with many plant species native to tropical regions, Strophanthus kombe faces threats from habitat destruction and overharvesting. Conservation efforts are necessary to ensure the sustainability of this species, both for its ecological role and its potential medicinal value.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD