TAG-72 antigen

TAG-72 antigen is a tumor-associated antigen that is expressed in a variety of human cancers, including ovarian cancer, breast cancer, colon cancer, and pancreatic cancer. It is a high molecular weight, mucin-like glycoprotein that is found on the surface of cancer cells and in the serum of patients with cancer. The antigen is used as a marker for the detection and monitoring of cancer.

Structure

TAG-72 antigen is a glycoprotein with a high molecular weight. It is a mucin-like protein, which means it has a high content of carbohydrates and is heavily glycosylated. The protein is composed of repeating units of a 20 amino acid sequence.

Expression in cancer

TAG-72 antigen is expressed in a variety of human cancers. It is found on the surface of cancer cells and in the serum of patients with cancer. The antigen is used as a marker for the detection and monitoring of cancer. It is particularly useful in the detection of ovarian cancer, breast cancer, colon cancer, and pancreatic cancer.

Clinical significance

The presence of TAG-72 antigen in the serum of patients with cancer can be used as a marker for the detection and monitoring of the disease. It can also be used to monitor the response to treatment. In addition, the antigen can be targeted for therapy, for example, by using monoclonal antibodies that bind to the antigen and deliver a toxic payload to the cancer cells.

See also

• Tumor marker
• Cancer immunotherapy
• Monoclonal antibodies in cancer therapy

TAG-72 antigen Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski