Tetraethylammonium bromide

Tetraethylammonium bromide is a quaternary ammonium compound with the chemical formula C₈H₂₀BrN. It is a white, crystalline salt that is highly soluble in water and various organic solvents. Tetraethylammonium bromide is widely used in scientific research for its ability to block potassium channels in cells, making it a valuable tool in the study of cellular physiology and neuroscience.

Properties

Tetraethylammonium bromide has a melting point of approximately 285°C and is highly soluble in water, which makes it useful in a variety of laboratory and industrial applications. Its ability to block potassium channels allows researchers to study the function of these channels in controlling the electrical activity of cells, particularly in neurons and muscle cells.

Applications

In neuroscience, tetraethylammonium bromide is used to study the role of potassium channels in nerve impulse transmission. By blocking these channels, researchers can investigate how neurons communicate and how this communication can be altered in various diseases. In addition, tetraethylammonium bromide has been used in the study of cardiac physiology, as potassium channels also play a critical role in the regulation of heart rate and rhythm.

Safety

As with many chemical compounds, handling tetraethylammonium bromide requires caution. It should be used in a well-ventilated area, and appropriate personal protective equipment (PPE) such as gloves and eye protection should be worn to avoid exposure.

See Also

• Quaternary ammonium compound
• Potassium channel
• Cellular physiology
• Neuroscience