Trimethylsilanol
Trimethylsilanol is a chemical compound with the formula (CH3)3SiOH. It is a colorless liquid that is used as a precursor to other organosilicon compounds.
Structure and properties[edit | edit source]
Trimethylsilanol is a tetrahedral molecule. The Si-O bond length is 1.64 Å, and the Si-O-H angle is 109.5°. The molecule has a dipole moment of 1.9 D due to the polar Si-O bond. The compound is a weak acid, with a pKa of 11.0 in water.
Synthesis[edit | edit source]
Trimethylsilanol can be synthesized by the hydrolysis of trimethylsilyl chloride, using water or a weak base such as ammonia. The reaction is as follows:
(CH3)3SiCl + H2O → (CH3)3SiOH + HCl
Uses[edit | edit source]
Trimethylsilanol is used as a precursor to other organosilicon compounds. It can be converted to trimethylsilyl chloride by reaction with hydrochloric acid, or to trimethylsilyl ethers by reaction with alcohols. It is also used as a protecting group in organic synthesis, particularly for alcohols and carboxylic acids.
Safety[edit | edit source]
Trimethylsilanol is a flammable liquid and a mild irritant. It should be handled with care, using appropriate personal protective equipment.
See also[edit | edit source]
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.Contributors: Prab R. Tumpati, MD