U-48800

From WikiMD's Food, Medicine & Wellness Encyclopedia

U-48800 is a synthetic opioid that is part of the U-series of opioids. It was first developed in the 1970s by a team at Upjohn, a pharmaceutical company, which is reflected in the 'U' in its name. U-48800 is a structural analog of the earlier opioid AH-7921 and has been sold as a designer drug.

Chemistry[edit | edit source]

U-48800 is a member of the drug class known as U-series opioids. These drugs are characterized by a common backbone structure, which is modified to create different analogs. U-48800 is a structural analog of AH-7921, meaning it shares a similar chemical structure but has been modified.

Pharmacology[edit | edit source]

Like other opioids, U-48800 acts on the mu-opioid receptor, producing effects such as analgesia, sedation, and euphoria. However, the exact mechanism of action and pharmacokinetics of U-48800 are not well understood, as it has not been extensively studied in humans.

Effects[edit | edit source]

The effects of U-48800 are similar to those of other opioids and include analgesia, sedation, euphoria, and respiratory depression. However, due to its status as a designer drug and lack of clinical studies, the exact effects and safety profile of U-48800 are not well known.

Legal Status[edit | edit source]

U-48800 is a controlled substance in several countries, including the United States, where it is classified as a Schedule I drug under the Controlled Substances Act. This means it has a high potential for abuse and no accepted medical use.

Health Risks[edit | edit source]

As with other opioids, U-48800 carries a risk of overdose, which can result in respiratory depression, coma, and death. There have been several reported deaths associated with U-48800 use.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD