UQCRQ

UQCRQ (Ubiquinol-Cytochrome C Reductase Complex III Subunit VII) is a protein that in humans is encoded by the UQCRQ gene. This protein is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome bc1 complex), which is part of the mitochondrial respiratory chain.

Function

The UQCRQ protein is one of several proteins that form the ubiquinol-cytochrome c reductase complex, an essential part of the mitochondrial respiratory chain. This complex, which is also known as complex III, is responsible for the transfer of electrons from ubiquinol to cytochrome c, a process that is essential for cellular respiration.

Clinical significance

Mutations in the UQCRQ gene have been associated with mitochondrial complex III deficiency, a rare genetic disorder that can cause a variety of clinical symptoms, including muscle weakness, growth retardation, and lactic acidosis.

See also

• Mitochondrial disease
• Cytochrome c
• Ubiquinol

External links

• UQCRQ at the National Center for Biotechnology Information

‎

---

Translate: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, தமிழ், తెలుగు, Urdu, ಕನ್ನಡ, Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, বাংলা
European español, Deutsch, français, Greek, português do Brasil, polski, română, русский, Nederlands, norsk, svenska, suomi, Italian
Middle Eastern & African عربى, Turkish, Persian, Hebrew, Afrikaans, isiZulu, Kiswahili,
Other Bulgarian, Hungarian, Czech, Swedish, മലയാളം, मराठी, ਪੰਜਾਬੀ, ગુજરાતી, Portuguese, Ukrainian