Xanomeline/trospium

Xanomeline is a muscarinic acetylcholine receptor agonist with a high affinity for the M1 and M4 subtypes. It has been studied for its potential use in the treatment of Alzheimer's disease, schizophrenia, and other medical conditions.

Pharmacology

Xanomeline is a muscarinic receptor agonist, meaning it binds to and activates certain receptors in the body. Specifically, it has a high affinity for the M1 and M4 subtypes of the muscarinic acetylcholine receptor. These receptors are found in various parts of the body, including the brain, where they play a role in memory and learning.

Clinical uses

Xanomeline has been studied for its potential use in the treatment of Alzheimer's disease and schizophrenia. In clinical trials, it has shown promise in improving cognitive function and reducing psychotic symptoms. However, further research is needed to confirm these findings and determine the optimal dosing regimen.

Side effects

Like all medications, xanomeline can cause side effects. The most common ones include dry mouth, constipation, and blurred vision. These are typically mild and go away on their own. However, if they persist or become severe, medical attention should be sought.

Trospium is an antimuscarinic drug used to treat overactive bladder. It works by blocking the action of acetylcholine, a neurotransmitter that causes muscles in the bladder to contract.

Pharmacology

Trospium is an antimuscarinic drug, meaning it blocks the action of acetylcholine at muscarinic receptors. This reduces the contraction of the bladder muscles, helping to control symptoms of overactive bladder.

Clinical uses

Trospium is used to treat overactive bladder, a condition characterized by frequent urination, urgency, and incontinence. It can help reduce these symptoms and improve quality of life.

Side effects

Common side effects of trospium include dry mouth, constipation, and blurred vision. These are usually mild and go away on their own. However, if they persist or become severe, medical attention should be sought.

See also

• Muscarinic acetylcholine receptor
• Antimuscarinic
• Overactive bladder