Zinc finger protein 157

Zinc finger protein 157 (ZNF157) is a protein that in humans is encoded by the ZNF157 gene. This protein is a member of the zinc finger protein family, which are characterized by the presence of zinc finger domains. These domains are known for their ability to bind to specific sequences of DNA, and play a crucial role in gene regulation.

Structure

ZNF157 is a nuclear protein that contains several C2H2-type zinc fingers. The C2H2-type zinc finger is a common type of zinc finger domain, which is characterized by two cysteine residues and two histidine residues that coordinate a zinc ion. This structure allows the protein to interact with DNA, RNA, protein and/or lipid substrates.

Function

The exact function of ZNF157 is not fully understood. However, like other zinc finger proteins, it is believed to play a role in gene regulation. Zinc finger proteins can act as transcription factors, binding to specific sequences of DNA and influencing the transcription of associated genes. This can affect a variety of cellular processes, including cell growth, differentiation, and apoptosis.

Clinical significance

While the specific role of ZNF157 in human health and disease is not yet fully understood, zinc finger proteins more broadly have been implicated in a variety of diseases, including cancer, autoimmune diseases, and neurodegenerative diseases. Further research is needed to elucidate the specific role of ZNF157 in these and other conditions.

See also

• Zinc finger
• Zinc finger domain
• Zinc finger protein
• Gene regulation
• Transcription factor

References

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