Zinc finger protein 717

Zinc finger protein 717 (ZNF717) is a protein that in humans is encoded by the ZNF717 gene. This protein belongs to the zinc finger protein family, a group of proteins characterized by the presence of zinc finger domains. These domains are known for their ability to bind to specific sequences of DNA, playing a crucial role in gene regulation.

Structure

ZNF717 is a member of the C2H2-type zinc finger protein family. The C2H2-type zinc finger domain is a common type of protein domain that functions as an interaction module. It is characterized by the presence of two cysteine residues and two histidine residues that coordinate a zinc ion, giving the domain its name.

Function

ZNF717 is believed to act as a transcription factor, a protein that regulates the transcription of genetic information from DNA to RNA. By binding to specific DNA sequences, ZNF717 can control the activity of certain genes, influencing various biological processes.

Clinical Significance

While the exact role of ZNF717 in human health and disease is still under investigation, alterations in the function or expression of zinc finger proteins have been implicated in a number of diseases, including cancer, autoimmune diseases, and neurodegenerative diseases.

See Also

• Zinc finger
• Transcription factor
• Protein domain
• Gene regulation

References

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