CYP4X1

CYP4X1 is a gene that encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33.

Function

CYP4X1 is a member of the cytochrome P450 family of enzymes, which are involved in the metabolism of a wide variety of substances, including drugs, toxins, and endogenous compounds. The specific function of CYP4X1 is not well understood, but it is thought to play a role in the metabolism of fatty acids and other lipids.

Structure

The CYP4X1 gene is located on the short (p) arm of chromosome 1 at position 33. The gene spans approximately 50 kilobases and consists of 13 exons. The encoded protein is 60 kDa in size and is localized in the endoplasmic reticulum.

Clinical significance

Alterations in the CYP4X1 gene have been associated with various diseases, including cancer, neurological disorders, and cardiovascular disease. However, the exact role of CYP4X1 in these diseases is not fully understood and is the subject of ongoing research.

Research

Research into the function and clinical significance of CYP4X1 is ongoing. Current areas of investigation include the role of CYP4X1 in drug metabolism, its potential as a target for drug therapy, and its involvement in disease processes.

See also

• Cytochrome P450
• Drug metabolism
• Chromosome 1 (human)

References

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