Minimally invasive adenocarcinoma of the lung

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Minimally Invasive Adenocarcinoma of the Lung (MIA) is a subtype of lung cancer characterized by its small size (3 cm or less in diameter) and limited invasion into the surrounding lung tissues. It is a form of adenocarcinoma, which is a type of cancer that forms in mucus-secreting glands throughout the body, including the lungs. MIA is considered an early stage of lung adenocarcinoma and has a better prognosis compared to more invasive forms of lung cancer.

Diagnosis[edit | edit source]

The diagnosis of Minimally Invasive Adenocarcinoma of the Lung often involves a combination of imaging studies and tissue biopsy. Computed tomography (CT) scans are commonly used to identify the presence of a lung nodule or mass. If a suspicious lesion is identified, a biopsy is required to confirm the diagnosis. Techniques for obtaining a biopsy include bronchoscopy, CT-guided biopsy, and video-assisted thoracoscopic surgery (VATS). Histologically, MIA is characterized by a predominant lepidic growth pattern with minimal invasion (≤5 mm) into the surrounding lung parenchyma.

Treatment[edit | edit source]

The primary treatment for Minimally Invasive Adenocarcinoma of the Lung is surgical resection. Options include lobectomy, which is the removal of an entire lobe of the lung, or a limited resection, such as segmentectomy or wedge resection, for smaller tumors. The choice of surgery depends on the tumor's size, location, and the patient's overall health and lung function. In some cases, adjuvant therapy, such as chemotherapy, may be recommended after surgery, especially if there is a higher risk of recurrence.

Prognosis[edit | edit source]

Patients diagnosed with Minimally Invasive Adenocarcinoma of the Lung generally have a favorable prognosis, with higher survival rates compared to more advanced stages of lung cancer. The 5-year survival rate for patients with MIA is significantly higher than that for patients with more invasive forms of lung adenocarcinoma. Early detection and treatment are key factors that contribute to the positive outcome.

Epidemiology[edit | edit source]

Minimally Invasive Adenocarcinoma of the Lung is more commonly diagnosed in individuals who are at an early stage of lung cancer. It is often found incidentally during imaging studies for other reasons, given its small size and lack of symptoms in early stages. The incidence of MIA has increased with the widespread use of high-resolution imaging techniques, which can detect smaller lung nodules.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD