PPADS

PPADS (Pyridoxal-phosphate-adinosine diphosphate-sulfate) is a pharmacological substance that acts as a selective P2X receptor antagonist. It is commonly used in scientific research to help understand the function of these receptors.

Pharmacology

PPADS is a non-selective, competitive antagonist at P2X receptors. It has been shown to inhibit responses to ATP at all seven P2X receptor subtypes, although it is most potent at the P2X1, P2X3, and P2X2/3 subtypes. PPADS does not inhibit responses to ATP at P2Y receptors.

Uses in Research

PPADS is used in scientific research to help understand the function of P2X receptors. It has been used in studies investigating the role of these receptors in a variety of physiological processes, including neurotransmission, inflammation, and pain perception.

See Also

• P2X purinoreceptor
• Antagonist
• ATP

References

PPADS Resources
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