Stearidonic acid

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Stearidonic acid

Stearidonic acid, also known as 18:4 n-3, is an ω-3 polyunsaturated fatty acid. It is a precursor in the biosynthesis of longer-chain ω-3 fatty acids such as eicosapentaenoic acid (EPA). Stearidonic acid is considered an important nutrient due to its potential health benefits.

Properties[edit | edit source]

Stearidonic acid is a 18-carbon chain fatty acid with four double bonds, located at the 6th, 9th, 12th, and 15th carbon positions. Its chemical formula is C18H30O2. Stearidonic acid is commonly found in plant oils, particularly in certain species of algae and seeds.

Biological Importance[edit | edit source]

Stearidonic acid is a precursor to EPA, a long-chain ω-3 fatty acid that plays a crucial role in various physiological processes, including inflammation regulation, cardiovascular health, and brain function. The conversion of stearidonic acid to EPA is more efficient compared to the conversion of alpha-linolenic acid (ALA) to EPA.

Dietary Sources[edit | edit source]

Dietary sources of stearidonic acid include oils from plants such as blackcurrant seed oil, echium oil, and hemp seed oil. These oils are often used as supplements to increase the intake of ω-3 fatty acids in the diet.

Health Benefits[edit | edit source]

Consumption of stearidonic acid has been associated with various health benefits, including reducing inflammation, improving cardiovascular health, and supporting cognitive function. Studies have shown that stearidonic acid supplementation may help in managing conditions such as arthritis and cardiovascular diseases.

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD