Tapinarof
From WikiMD's Food, Medicine & Wellness Encyclopedia
What is Tapinarof?[edit | edit source]
- Tapinarof (vtama) is an aryl hydrocarbon receptor agonist used to treat plaque psoriasis.
What are the uses of this medicine?[edit | edit source]
- Tapinarof (vtama) cream is a prescription medicine used on the skin (topical) to treat plaque psoriasis in adults.
How does this medicine work?[edit | edit source]
- Tapinarof is an aryl hydrocarbon receptor (AhR) agonist.
- The exact mechanisms by which vtama cream shows its therapeutic action in psoriasis patients are unknown.
Who Should Not Use this medicine ?[edit | edit source]
- This medicine have no usage limitations.
What drug interactions can this medicine cause?[edit | edit source]
- No formal drug interaction studies have been conducted.
Is this medicine FDA approved?[edit | edit source]
- Tapinarof was approved for medical use in the United States in May 2022.
How should this medicine be used?[edit | edit source]
Recommended dosage:
- Apply a thin layer of vtama cream to affected areas once daily.
Administration:
- Apply a thin layer of vtama cream only to your psoriasis skin lesions 1 time a day. Avoid applying vtama cream to unaffected areas of your skin.
- Wash your hands after applying vtama cream unless you are using it to treat your hands.
- If someone else applies vtama cream for you, they should wash their hands after application.
What are the dosage forms and brand names of this medicine?[edit | edit source]
This medicine is available in fallowing doasage form:
- As Cream, 1%
- Each gram of vtama cream contains 10 mg of tapinarof.
This medicine is available in fallowing brand namesː
- vtama
What side effects can this medication cause?[edit | edit source]
The most common side effects of this medicine include:
- red raised bumps around the hair pores (folliculitis)
- pain or swelling in the nose and throat (nasopharyngitis)
- skin rash or irritation including itching and redness, peeling, burning, or stinging
- headache
- itching
- flu
What special precautions should I follow?[edit | edit source]
- Apply vtama cream once daily to psoriasis skin lesions only and avoid unaffected areas of skin.
- Wash hands after application unless vtama cream is for treatment of the hands.
- Advise patients that vtama cream is for external use only.
What to do in case of emergency/overdose?[edit | edit source]
- In case of overdose, call the poison control helpline of your country. In the United States, call 1-800-222-1222.
- Overdose related information is also available online at poisonhelp.org/help.
- In the event that the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services. In the United States, call 911.
Can this medicine be used in pregnancy?[edit | edit source]
- The available data on vtama cream use in pregnant women are insufficient to evaluate for a drug-associated risk of major birth defects, miscarriage, or other adverse maternal or fetal outcomes.
Can this medicine be used in children?[edit | edit source]
- Safety and efficacy of vtama cream have not been established in pediatric subjects with psoriasis under 18 years of age.
What are the active and inactive ingredients in this medicine?[edit | edit source]
- Active ingredient: tapinarof
- Inactive ingredients: benzoic acid, butylated hydroxytoluene, citric acid monohydrate, diethylene glycol monoethyl ether, edetate disodium, emulsifying wax, medium-chain triglycerides, polyoxyl 2 stearyl ether, polyoxyl 20 stearyl ether, polysorbate 80, propylene glycol, purified water, and sodium citrate dihydrate.
Who manufactures and distributes this medicine?[edit | edit source]
- Marketed by: Dermavant Sciences Inc., 3780 Kilroy Airport Way, Long Beach, CA
What should I know about storage and disposal of this medication?[edit | edit source]
- Store vtama cream at room temperature between 68°F to 77°F (20°C to 25°C).
- Do not freeze vtama cream.
- Protect vtama cream from exposure to excessive heat.
- Keep vtama cream and all medicines out of the reach of children.
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