Von economo's disease
Other names[edit | edit source]
Encephalitis lethargica
Pathophysiology[edit | edit source]
Encephalitis lethargica is a disease characterized by high fever, headache, double vision, delayed physical and mental response, and lethargy.
Symptoms[edit | edit source]
- In acute cases, patients may enter coma.
- Patients may also experience abnormal eye movements, upper body weakness, muscular pains, tremors, neck rigidity, and behavioral changes including psychosis.
Cause[edit | edit source]
- The cause of encephalitis lethargica is unknown.
- Between 1917 to 1928, an epidemic of encephalitis lethargica spread throughout the world, but no recurrence of the epidemic has since been reported.
- Postencephalitic Parkinson's disease may develop after a bout of encephalitis-sometimes as long as a year after the illness
Prognosis[edit | edit source]
The course of encephalitis lethargica varies depending upon complications or accompanying disorders.
Treatment[edit | edit source]
Treatment for encephalitis lethargica is symptomatic. Levodopa and other antiparkinson drugs often produce dramatic responses.
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Contributors: Prab R. Tumpati, MD