P2RY1

P2RY1 is a protein that in humans is encoded by the P2RY1 gene. This protein is a member of the G protein-coupled receptor family, and is a receptor for adenosine diphosphate (ADP).

Function

The product of this gene, P2RY1, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ADP.

Clinical significance

Mutations in the P2RY1 gene have been associated with various pathological conditions, including bleeding disorders and platelet dysfunction.

See also

• P2Y receptor
• G protein-coupled receptor
• Adenosine diphosphate

External links

• GeneCards: P2RY1

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