OR2T1

OR2T1 is a gene that encodes the olfactory receptor, family 2, subfamily T, member 1 protein in humans. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome.

Function

The protein encoded by the OR2T1 gene is an olfactory receptor, a type of protein that plays a role in the sense of smell. These receptors, which are located in the cell membranes of olfactory receptor neurons, detect odor molecules in the nose and then send signals to the brain, which interprets these signals as specific smells.

Clinical Significance

While the specific function and clinical significance of OR2T1 are not yet fully understood, olfactory receptors in general are known to play a crucial role in the sense of smell. Disruptions in the function of these receptors can lead to conditions such as anosmia (loss of the sense of smell) and hyposmia (reduced ability to smell).

See Also

• Olfactory receptor
• Anosmia
• Hyposmia

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