OR6P1

OR6P1 is a gene that encodes a protein in humans. The OR6P1 gene is also known as olfactory receptor, family 6, subfamily P, member 1. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.

Function

Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Clinical significance

While the specific function and clinical significance of OR6P1 are not fully understood, olfactory receptors in general play a crucial role in the olfactory system, which has been linked to a variety of health conditions. For example, changes in the olfactory system can be an early indicator of neurodegenerative diseases like Parkinson's disease and Alzheimer's disease.

See also

• Olfactory receptor
• G protein-coupled receptor
• Olfactory system

External links

• OR6P1 at NCBI Gene

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